Director/Sr. Director, Information Technology
Manifoldbio · Boston
About this role
**Manifold Bio — Director/Sr. Director, Information Technology** *Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems.* ## Position Manifold Bio is looking for its first dedicated IT leader to keep a fast, highly technical company secure and scalable as it grows. This is a hands-on role where you configure systems, fix what breaks, and set standards—without inheriting a large team or a finished playbook. You’ll take ownership of an IT program already in motion (SSO, security awareness, a new network, runbooks, and a working plan) from your first week. You’ll work closely with the COO, cloud and data engineers, AI and computational scientists, and the lab automation team—earning trust by being useful first, then advocating for change in plain language. ## Responsibilities ### Run IT - Own day-to-day IT for everyone across offices and labs (Mac and Windows) and be the go-to person. - Administer identity and productivity tools: Okta, Google Workspace, Slack, device management, and the password manager. - Run onboarding and offboarding so access is ready on day one and removed the same day someone leaves. - Maintain accurate records of devices, applications, licenses, and owners; reclaim unused resources. - Keep conference rooms, printing, and everyday tools working so nobody loses time. ### Lead security - Own the security program: phishing-resistant sign-in, endpoint protection, awareness training and phishing tests, incident response, and tabletop exercises. - Respond to security questionnaires and partner diligence requests with evidence. - Enforce least privilege for everyone, including executives and administrators. - Ensure cyber insurance requirements are met and evidence is ready for renewals. ### Enable science and AI - Partner with cloud and data engineers on AWS identity, access, logging, and backup (you set guardrails; they run the platform). - Help determine how AI agents access data and systems—maintaining pace without exposing the company. ### Infrastructure, vendors, and budget - Own the network across two floors with a network partner. - Run backup and recovery for cloud, storage, and SaaS data, including scheduled restore tests. - Keep lab instruments connected and patched on a schedule that respects their runs; ensure recoverability with lab automation. - Manage IT service providers and contractors against clear service levels. - Build and run the IT budget; recommend when to add people or services; route purchases through Manifold’s approval process. ### Grow the function - Write and maintain standards and runbooks so IT scales with the company. - Partner with Quality as programs move toward the clinic so IT practices are ready for required controls. - Build IT’s multi-year roadmap and investment plan with the COO and finance, aligned to hiring, space, and clinical plans. ## Your First Year - **First 90 days:** Take over a working program from the fractional CIO, learn how labs and computational teams work, and meet every team. - **By 6 months:** Run IT day to day independently, and own the security program, records, and runbooks. - **By end of year:** Deliver IT people trust, security that holds up to partner diligence, and a plan for the next stage of growth. ## Required Qualifications - 10+ years in IT, with at least 3 in a startup or high-growth compan
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