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Strategic Projects Lead - Engineering (Life Sciences & Chemical)

Afterquery · San Francisco

onsitelead$150,000–$225,000Posted Nov 6, 2026PythonCADEDAsimulationautomation

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About this role

**Strategic Projects Lead - Engineering (Life Sciences & Chemical)** **About AfterQuery** AfterQuery (https://www.afterquery.com/) is an applied research lab curating data solutions for foundation model development. We serve frontier AI labs with the mission of delivering the best data to power the best models—making expertise that once took a lifetime available to anyone who needs it. We’re based in San Francisco and backed by leading investors including Altos Ventures, BoxGroup, and Y Combinator, with angels from Google DeepMind, OpenAI, Anthropic, Meta Superintelligence Labs, and Microsoft AI. --- **Why Apply** - **Massive Opportunity:** Forbes reported we could be YC’s fastest unicorn, reportedly raising at a $3.2B valuation. - **Founding Impact:** Own and architect core infrastructure systems powering our platform from the ground up. - **Equity & Growth:** Competitive salary and meaningful equity; help shape the engineering organization as we scale. - **Strong Team:** Founding team experience from Citadel Securities, Meta, Google, Silver Lake, and Morgan Stanley. --- **Key Responsibilities** - **Project & client management:** Partner with leading AI organizations to build next-generation data solutions that push model capability and drive revenue. - **Manage expert teams across technical domains:** Lead and coordinate specialized contributors across areas such as electrical engineering, mechanical engineering, semiconductors, hardware design, and more. - **Shape how AI systems are trained:** Design dataset specifications that influence how frontier models are evaluated and improved. - **Drive high-impact execution end-to-end:** Own critical projects from scoping through delivery—breaking down complex problems, iterating quickly, and shipping in a fast-moving environment. - **Gain top-tier operational experience:** Support operational initiatives across the business, working across building, analyzing, coordinating, and executing as needed. --- **Required Qualifications** - Bachelor’s degree or higher in Electrical Engineering, Computer Engineering, Mechanical Engineering, Industrial Engineering, Systems Engineering, or a closely related technical field. - 3+ years of experience in engineering, technical research, hardware development, or software engineering roles involving physical systems. - Strong technical problem-solving skills: break down unfamiliar problems, understand constraints, and reason through complex systems. - Hands-on engineering experience designing, building, simulating, testing, or investigating substantial technical projects. - Familiarity with engineering design, simulation, testing, or verification processes. - High agency and strong work ethic; comfortable defining problems and thriving with minimal direction in ambiguous situations. - Demonstrated leadership excellence and strong communication abilities. - Passion for AI and an entrepreneurial mindset. --- **Preferred Qualifications** - Experience in semiconductors, chip design, electronic circuits, PCB design, CAD, hardware engineering, manufacturing, or engineering automation. - Python proficiency; experience with engineering software, CAD/EDA tools, simulation environments, or technical automation workflows. - Experience with physical systems, engineering design, or applied technical research (professional work, internships, or independent projects). - Strong coding abilities and/or experience building tools/workflows to automate engineering pr

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