Senior Software Engineer, Site Reliability
Freenome · Remote
About this role
**About this opportunity** Do you have what it takes to be a **Freenomer**? A “Freenomer” is a determined, mission-driven, results-oriented employee fueled by the opportunity to change the landscape of cancer and make a positive impact on patients’ lives. Our **Site Reliability Engineering (SRE)** team is a new and critical function at Freenome. As a founding member, you’ll help define the culture and build the systems that keep our regulated, cloud-based production environments reliable as we transition from research to commercial operations. We value: - **Reliability as a product feature** - **Continual improvement and learning** - **Automate all the things!** - **Technical simplicity and clarity** - **Blameless postmortems and transparent communication** **What you’ll do** As a Site Reliability Engineer, you will help design, implement, and operate **observability, reliability, and incident management** systems and practices across our clinical lab systems and regulated commercial workloads. You’ll partner with engineering teams to define **SLIs**, **SLOs**, and **error budgets**; build **runbooks** and **operational playbooks**; and develop the monitoring and automation needed to ensure systems are reliable and compliant. This will also include contributions to **system code**, **infrastructure deployments**, and **automation**. **Key responsibilities** - Define and implement observability practices (metrics, traces, dashboards, logs, alerts) - Partner with product, engineering, and lab teams to develop and maintain incident response playbooks and escalation procedures - Define SLIs/SLOs and establish error budgets - Participate in on-call rotation; champion automation and self-healing - Contribute to production deployment and change-management processes that meet **FDA** and compliance requirements - Automate operational tasks to reduce manual intervention - Contribute to production systems and designs to improve reliability - Use **Infrastructure as Code (IaC)** to manage and deploy team-owned infrastructure and subsystems - Help build out the SRE practice - Work closely with engineering, product, and lab teams to understand service reliability needs - Partner with TPMs, RA/QA, and compliance stakeholders to align operational practices with regulatory requirements - Participate in cross-functional incident reviews and postmortems - Share knowledge and document operational standards for consistency and onboarding - Design and run fire drills/tabletop exercises and disaster recovery exercises - Independently drive reliability improvements in scoped systems or services - Provide mentorship on observability, incident management, and operational best practices - Help evolve Freenome’s reliability practices and contribute to team strategy discussions **Must haves** - Bachelor’s degree in Computer Science, Engineering, or equivalent experience - 5+ years in software engineering or Infra/DevOps/SRE roles (**Python or Go preferred**) - Experience deploying cloud infrastructure via automation (e.g., **Terraform, Pulumi, Bicep/ARM**) - Hands-on experience operating production workloads in cloud environments - Familiarity with **Kubernetes** (AKS, GKE, or EKS) - Strong troubleshooting and root-cause analysis skills in distributed systems - Experience with observability platforms (e.g., **Datadog, Prometheus/Grafana, OpenTelemetry**) - Ability to define and implement metrics, dashboards, and alerting - Demonstrated ability to work auto
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