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Staff Software Engineer

Weave · San Francisco Bay Area, CA

hybridstaff$200,000–$250,000Posted Oct 27, 2026PythonDjangoPostgresRedisLLMsGo

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About this role

**Why Weave Exists** At Weave, our mission is to evolve how therapeutic knowledge is captured, transformed, and communicated throughout drug development—equipping human experts with AI instruments so drugs can reach patients as rapidly, safely, and inexpensively as possible. The Weave Platform streamlines regulatory workflows end-to-end by infusing every step with AI, helping design and build the AI workbench for the entire therapeutic lifecycle. **The Role & Your Mission** We’re looking for a **Staff Backend Engineer** reporting to the Backend Engineering Manager. You’ll navigate between **data, AI, and backend systems**, with core responsibility for the **stability, performance, and reliability** of the AI system. You’ll develop novel solutions to customer problems, characterize results, and deliver solutions into production—moving smoothly from **idea → experiment → testing → production**. We value solving problems over buzzwords, and we prefer **simple, well-tested, stable** solutions that are dependable and impressive. **What You’ll Own** - Understand customer problems and translate them into simple solutions - Partner with Product and Design to quickly find solutions - Write performant, simple code (Django + Python + Postgres + Redis) - Manage ongoing conceptual and technical complexity while delivering value on Product projects **What You’ll Bring** - Experience at an early-stage, product-based startup (under 50 people) - **8+ years** of Django experience in production - Experience using **LLMs in production** - Direct interaction with LLMs without abstraction libraries - Humble, hungry, and smart - Ability to move quickly while producing high-quality results - Pragmatic, analytical thinker; efficient decision maker **Bonus** - Worked on a product in a regulated domain or where data privacy + security were essential - BS in Computer Science (or similar) preferred **What We Offer** - 🎯 Work at a modern healthcare technology company with meaningful impact - 🏆 Competitive salary **($200,000–$250,000)** and equity packages - 🧬 Comprehensive health, dental, and vision insurance - 🏝️ Generous PTO, parental leave, and benefits including OneMedical, TalkSpace, Teladoc - 🚀 Career development opportunities as the company enters a growth phase - 🌎 Hybrid in San Francisco (in-office Tue/Wed/Thurs) with flexibility to work remote Mon/Fri **Equal Opportunity Employer** We’re committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. This organization participates in **e-Verify**.

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